Anti-Cytokeratin 18(DA7), CF640R conjugate
This MAb reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It was reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18._x000D_ _x000D_ Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors._x000D_ _x000D_
Product Specifications
Synonyms
Cell Proliferation-inducing Gene 46 Protein; CK18; CYK18 Cytokeratin Endo B; K18; Keratin-18; Kerd; KRT18
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
KRT18
Gene ID
3875
NCBI Gene ID
406013
UniProt
P05783
Cellular Locus
Cytoskeleton
Host
Mouse
Species Reactivity
Human
Immunogen
Human breast cancer PMC 42 cells
Target Antigen
Cytokeratin 18
Clonality
Monoclonal
Isotype
IgG1 κ
Clone
DA7
Conjugation
CF640R
Disease
Tumor
Source
Animal
Applications
IF (verified) | IHC, FFPE (verified) | WB (verified)
Validated Applications
IF,IHC,FFPE,WB
Field of Research
Cancer, Cytoskeleton
Positive Control
MCF-7, HeLa cells, Breast Cancer
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
45 kDa
Additionnal Information
Shipping Conditions
Room temperature
Storage Conditions
4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/877133/datasheet/bnc400198-500.pdf
Product MSDS
https://cdn.gentaur.com/products/37/877133/msds/bnc400198-500.pdf
CAS Number
9007-83-4
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