Rovanersen
Rovanersen (WVE-120101) is an antisense oligonucleotide that specifically targets mutated mRNA copies of the huntington (HTT) gene without affecting healthy mRNA of HTT gene, thereby preventing the production of faulty Huntingtin protein. Rovanersen can be used for huntington’s disease research[1].
Product Specifications
CAS Number
[2072901-32-5]
Product Name Alternative
WVE-120101
UNSPSC
12352208
Target
Huntingtin
Type
Oligonucleotides
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/rovanersen.html
Purity
94.24
Solubility
H2O : ≥ 50 mg/mL
Smiles
[Rovanersen]
Molecular Formula
C202H259N82O111P19S13
Molecular Weight
6617.00
References & Citations
[1]M Meena, et al. Selectivity and Biodistribution of WVE-120101, a Potential Antisense Oligonucleotide Therapy for the Treatment of Huntington’s Disease (S56.001) . AAN Enterprises. April 18, 2017; 88 (16 Supplement) .
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Oligonucleotides
Clinical Information
Phase 2
Available Sizes
Curated Selection
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