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Anti-CD70(TNFS7/1026)

This antibody recognizes a protein of 30 kDa, identified as CD70. It is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T- and B-lymphocytes. It induces proliferation of co-stimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Specifications

Synonyms

CD27 ligand (CD27L); CD27LG; Ki24; Surface antigen CD70; Tumor necrosis factor (ligand) superfamily, member 7 (TNFSF7)

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

CD70

Gene ID

970

NCBI Gene ID

501497; 715224

UniProt

P32970

Cellular Locus

Plasma membrane

Host

Mouse

Species Reactivity

Human

Immunogen

Recombinant human CD70 protein

Target Antigen

CD70

Clonality

Monoclonal

Isotype

IgG1 κ

Clone

TNFS7/1026

Conjugation

Purified, BSA-free

Source

Animal

Field of Research

Cytokines, Immunology

Positive Control

Raji cells. Lymph node or tonsil.

Concentration

1 mg/mL

Buffer

PBS, no BSA, no azide

Molecular Weight

~30 kDa

Additionnal Information

For coating for ELISA, order Ab without BSA|Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Optimal dilution and staining procedure for a specific application should be determined by user|Recommended starting concentrations for titration are 1-2 ug/mL for most applications, or 1 ug/million cells/100 uL for flow cytometry

Shipping Conditions

Room temperature

Storage Conditions

-35°C to -5°C ; Stable at room temperature or 37°C (98°F) for 7 days.

Shelf Life

2 years

Product Datasheet

https://cdn.gentaur.com/products/37/874073/datasheet/bnum1026-50.pdf

Product MSDS

https://cdn.gentaur.com/products/37/874073/msds/bnum1026-50.pdf

CAS Number

9007-83-4

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