HDAC8-IN-7
Product Specifications
UNSPSC Description
HDAC8-IN-7 (H7E), a HDAC8 inhibitor, exerts retinoprotective effects against glaucomatous injury via ameliorating aberrant Müller glia activation and oxidative stress. HDAC8-IN-7 alleviates functional and structural defects within the inner retina[1].
Target Antigen
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Epigenetics
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/hdac8-in-7.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=C(/C=C/C(NO)=O)C(NC2=CC=C(OC)C(OC)=C2)=C1
Molecular Weight
344.36
References & Citations
[1]Liang-Huan Wu, et al. A novel HDAC8 inhibitor H7E exerts retinoprotective effects against glaucomatous injury via ameliorating aberrant Müller glia activation and oxidative stress. Biomed Pharmacother. 2024 Apr 4:174:116538.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-161465/HDAC8-IN-7-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-161465/
Clinical Information
No Development Reported
Curated Selection
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