HDAC8-IN-7

HDAC8-IN-7 (H7E), a HDAC8 inhibitor, exerts retinoprotective effects against glaucomatous injury via ameliorating aberrant Müller glia activation and oxidative stress. HDAC8-IN-7 alleviates functional and structural defects within the inner retina[1].

Product Specifications

UNSPSC

12352005

Target

HDAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

COVID-19-anti-virus

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/hdac8-in-7.html

Solubility

10 mM in DMSO

Smiles

COC1=CC=C(/C=C/C(NO)=O)C(NC2=CC=C(OC)C(OC)=C2)=C1

Molecular Formula

C18H20N2O5

Molecular Weight

344.36

References & Citations

[1]Liang-Huan Wu, et al. A novel HDAC8 inhibitor H7E exerts retinoprotective effects against glaucomatous injury via ameliorating aberrant Müller glia activation and oxidative stress. Biomed Pharmacother. 2024 Apr 4:174:116538.