SulfoxFluor

SulfoxFluor is a fluorinated sulfoximine compound that can be used in the rapid deoxyfluorination and selective deoxyazidation reactions of various alcohols. SulfoxFluor is characterized by high reactivity, rapid reaction, simple operation, easy scale-up, and high selectivity[1][2][3][4].

Product Specifications

CAS Number

[2143892-50-4]

UNSPSC

12352005

Hazard Statement

H302, H315, H318, H335

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/sulfoxfluor.html

Concentration

10mM

Purity

99.53

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=S(N=S(F)(C1=CC=C(C=C1)Cl)=O)(C2=CC=C(C)C=C2)=O

Molecular Formula

C13H11ClFNO3S2

Molecular Weight

347.82

Precautions

H302, H315, H318, H335

References & Citations

[1]Guo J, et al. Rapid Deoxyfluorination of Alcohols with N-Tosyl-4-chlorobenzenesulfonimidoyl Fluoride (SulfoxFluor) at Room Temperature. Chemistry. 2019;25 (30) :7259-7264.|[2]Guo J, et al. SulfoxFluor-enabled deoxyazidation of alcohols with NaN3[J]. Nat Commun. 2022 May 18;13 (1) :2752. |[3]Renxiang Liu, et al. Modified and Scalable Synthesis of N-Tosyl-4-Chlorobenzenesulfonimidoyl Fluoride (SulfoxFluor) : Direct Imidation of Sulfinyl Chlorides with Chloramine-T Trihydrate[J]. American Chemical Society. 2022, 26, 2, 380-386.|[4]Jin P, et al. SulfoxFluor as a deoxyfluorination reagent, and beyond. Journal of Fluorine Chemistry, 2022, 261: 110029.