Anti-CD61(25E11.)
Reacts with human integrin beta3 (GPIIIa, vitronectin receptor beta chain). The protein detectable is a complex of CD41 and CD61.The apparent molecular weight of the GPIIIa by SDS-PAGE is 105 kDa reduced and 90 kDa unreduced. Ligands are fibronectin, fibrinogen, von Willebrand factor, vitronectin and thrombospondin. Residues 237-248 of GPIIIa or CD61 are critical in adhesive protein binding._x000D_ _x000D_ This antibody is available purified with BSA/azide at 200 ug/mL, or BSA/azide-free at 1 mg/mL.
Product Specifications
Synonyms
BDPLT2; GP3A; GPIIIa; GT; HPA 1; HPA 4; Integrin beta-3; ITGB3; NAIT; Platelet fibrinogen receptor beta subunit; Platelet glycoprotein IIIa; PTP
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
ITGB3
Gene ID
3690
NCBI Gene ID
218040
UniProt
P05106
Cellular Locus
Plasma membrane
Host
Mouse
Species Reactivity
Human
Immunogen
Normal blood mononuclear cells activated by mixed lymphocyte reaction
Target Antigen
CD61
Clonality
Monoclonal
Isotype
IgM κ
Clone
2500000000000
Conjugation
Purified, BSA-free
Source
Animal
Field of Research
Cell adhesion
Positive Control
U937, KG1a, HEL cells, and human platelets in lymph nodes or tonsils.
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
105 kDa & 90 kDa
Additionnal Information
References & Citations
Shipping Conditions
Room temperature
Storage Conditions
-35°C to -5°C ; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/873199/datasheet/bnum1048-50.pdf
Product MSDS
https://cdn.gentaur.com/products/37/873199/msds/bnum1048-50.pdf
CAS Number
9007-83-4
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