MS7972
MS7972 is a small molecule that blocks human p53 and CREB binding protein association. MS7972 can almost completely block this BRD interaction at 50 μM[1].
Product Specifications
CAS Number
[352553-42-5]
Product Name Alternative
Nanchangmycin A,Nanchangmycin (free acid)
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
MDM-2/p53
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ms7972.html
Purity
99.81
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C(N(C(C)=O)C2=C3C=CC=C2)=C3CCC1
Molecular Formula
C14H13NO2
Molecular Weight
227.26
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Sachchidanand, et al. Target structure-based discovery of small molecules that block human p53 and CREB binding protein association. Chem Biol. 2006 Jan;13 (1) :81-90.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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