Anti-CD5 (Mantle Cell Lymphoma Marker)(B-B8), CF647 conjugate
This antibody recognizes a 67 kDa transmembrane protein which is identified as CD5. The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Note that this MAb is not suitable for frozen tissues.
Product Specifications
Synonyms
CD5 antigen (p56 62), LEU1, Ly12, LyA, Lymphocyte antigen T1/Leu-1, Lymphocyte glycoprotein T1/Leu1, T-cell surface glycoprotein CD5
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CD5
Gene ID
921
NCBI Gene ID
58685
UniProt
P06127
Cellular Locus
Plasma membrane
Host
Mouse
Species Reactivity
Human
Immunogen
T cells activated with PHA
Target Antigen
CD5
Clonality
Monoclonal
Isotype
IgG1 κ
Clone
B-B8
Conjugation
CF647
Disease
Tumor
Source
Animal
Applications
Functional studies (published) | Flow, surface (expected) | IF (expected)
Validated Applications
FC,IF
Field of Research
Immunology
Positive Control
293T, Ramos, or MOLT-4 Cells. Tonsil.
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
67 kDa
Additionnal Information
References & Citations
Shipping Conditions
Room temperature
Storage Conditions
4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/872044/datasheet/bnc470995-100.pdf
Product MSDS
https://cdn.gentaur.com/products/37/872044/msds/bnc470995-100.pdf
CAS Number
9007-83-4
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