Anti-CD47(IAP/964)
This antibody reacts with Ig domain of CD47 protein. CD47, originally named integrin-associated protein (IAP), is a 50 kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction._x000D_ _x000D_ Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors._x000D_ _x000D_
Product Specifications
Synonyms
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CD47
Gene ID
961
NCBI Gene ID
446414
UniProt
Q08722
Cellular Locus
Plasma membrane
Host
Mouse
Species Reactivity
Human,Mouse
Immunogen
Recombinant human IAP protein
Target Antigen
CD47
Clonality
Monoclonal
Isotype
IgG1 κ
Clone
IAP/964
Conjugation
Purified, with BSA
Source
Animal
Applications
Flow (verified) | IF (verified) | IHC, FFPE (verified)
Validated Applications
FC,IF,IHC,FFPE
Field of Research
Cell adhesion, Hematology, Neuroscience, Signal transduction
Positive Control
HUVEC, OVCA3 cells, Placenta, Brain and Ovarian Tumors
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
~50 kDa
Additionnal Information
Shipping Conditions
Room temperature
Storage Conditions
4°C; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/871905/datasheet/bnub0964-500.pdf
Product MSDS
https://cdn.gentaur.com/products/37/871905/msds/bnub0964-500.pdf
CAS Number
9007-83-4
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