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Anti-CD41a(ITGA2B/1036), CF568 conjugate

Reacts with a calcium-dependent complex of CD41/CD61, a dimer of 90 kDa and 140 kDa present on the membrane of normal platelets and megakaryocytes. CD41/CD61 is also known as platelet glycoprotein GPIIb/GPIIIa or integrin IIa/3. This complex is the receptor of fibrinogen, fibronectin and von Willebrand factor, and mediates platelet adhesion and aggregation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Specifications

Synonyms

BDPLT16; BDPLT2; GPalpha IIb; GT; HPA3; Integrin alpha IIb; ITGA2B; ITGAB; platelet fibrinogen receptor, alpha subunit; platelet glycoprotein IIb of IIb/IIIa complex

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

ITGA2B

Gene ID

3674

NCBI Gene ID

411312

UniProt

P08514

Cellular Locus

Plasma membrane

Host

Mouse

Species Reactivity

Human

Immunogen

Recombinant full-length human Integrin alpha IIb protein

Target Antigen

CD41a

Clonality

Monoclonal

Isotype

IgG1 κ

Clone

ITGA2B/1036

Conjugation

CF568

Source

Animal

Field of Research

Hematology

Positive Control

KG1a, HEL cells, and human platelets in lymph nodes or tonsils.

Concentration

0.1 mg/mL

Buffer

PBS, 0.1% BSA, 0.05% azide

Molecular Weight

90 kDa

Additionnal Information

For coating for ELISA, order Ab without BSA|Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Optimal dilution and staining procedure for a specific application should be determined by user|Recommended starting concentrations for titration are 1-2 ug/mL for most applications, or 1 ug/million cells/100 uL for flow cytometry

Shipping Conditions

Room temperature

Storage Conditions

4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.

Shelf Life

2 years

Product Datasheet

https://cdn.gentaur.com/products/37/870631/datasheet/bnc681036-500.pdf

Product MSDS

https://cdn.gentaur.com/products/37/870631/msds/bnc681036-500.pdf

CAS Number

9007-83-4

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