BayCysLT2
Product Specifications
UNSPSC Description
BayCysLT2, an isophthalic acid derivative, is a selective and potent cysteinyl leukotriene 2 (CysLT2) receptor antagonist with an IC50 value of 53 nM. BayCysLT2 inhibits calcium mobilization induced by leukotriene D4 in HEK293 cells expressing human CysLT2 receptors. BayCysLT2 reverses LTC4-induced increases in coronary artery perfusion pressure and decreases in contractility in isolated perfused guinea pig hearts[1][2].
Target Antigen
Leukotriene Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/baycyslt2.html
Smiles
OC(C1=CC=C(OCCCC2=CC=C(C=C2)OCCCCOC3=CC=CC=C3)C(C(NC4CC(C(O)=O)CCC4)=O)=C1)=O
Molecular Weight
589.68
References & Citations
[1]Michael Harter, et al. Isophtalic acid derivatives. US20060154912A1. 2009 March 03.|[2]Ni NC, et al. A selective cysteinyl leukotriene receptor 2 antagonist blocks myocardial ischemia/reperfusion injury and vascular permeability in mice. J Pharmacol Exp Ther. 2011 Dec;339(3):768-78.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-116326/BayCysLT2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-116326/
Clinical Information
No Development Reported
CAS Number
712313-33-2
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
NHFF-1123-HX66 Each
Cas9 Expressing Monkey Primary Ovarian Microvascular Endothelial Cells
Ask
View Details 
