Anti-CD10(FR4D11)
CD10 (also known as Common Acute Lymphocytic Leukemia Antigen (CALLA)) is a type II transmembrane protein. It is a cell surface enzyme with neutral metalloendopeptidase activity, which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Specifications
Synonyms
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
MME
Gene ID
4311
NCBI Gene ID
307734
UniProt
P08473
Cellular Locus
Plasma membrane
Host
Mouse
Species Reactivity
Human
Immunogen
Raji cells
Target Antigen
CD10
Clonality
Monoclonal
Isotype
IgG1 κ
Clone
FR4D11
Conjugation
Purified, with BSA
Disease
Tumor
Source
Animal
Applications
Flow (verified) | Flow, surface (published) | IF (published) | IF (verified)
Validated Applications
FC,FC,IF,IF
Field of Research
Immunology, Proteases
Positive Control
Tonsil, small intestine, kidney
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
100 kDa
Additionnal Information
References & Citations
Shipping Conditions
Room temperature
Storage Conditions
4°C; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/866244/datasheet/bnub0248-100.pdf
Product MSDS
https://cdn.gentaur.com/products/37/866244/msds/bnub0248-100.pdf
CAS Number
9007-83-4
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