Anti-Blood Group H Type 2 (CD173)(19-OLE)
This antibody is applicable for staining ABO blood group O. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. This antibody recognizes the blood group H type 2 antigens, trisaccharide Fuc-a-1-2Gal1-4GlcNAc-a-1. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. It is expressed on endothelial cells, epithelial cells and granulocytes. Increased expression of this antigen has been observed on some tumor tissues such as gastric carcinomas, urothelial carcinomas, and colon carcinomas.This antibody is available purified with BSA/azide at 200 ug/mL, or BSA/azide-free at 1 mg/mL.
Product Specifications
Synonyms
ABO Type O; Blood Group O; Blood Group H
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
ABO
Gene ID
28
NCBI Gene ID
654423
UniProt
P16442
Cellular Locus
Plasma membrane
Host
Mouse
Species Reactivity
Human
Immunogen
Mucinous colonic adenocarcinoma
Target Antigen
Blood Group H Type-2
Clonality
Monoclonal
Isotype
IgM κ
Clone
19-OLE
Conjugation
Purified, with BSA
Source
Animal
Applications
IHC, FFPE (verified)
Validated Applications
IHC,FFPE
Field of Research
Cancer, Hematology
Positive Control
KG1 cells or human colorectal carcinoma.
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
Multiple
Additionnal Information
Shipping Conditions
Room temperature
Storage Conditions
4°C; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/865691/datasheet/bnub0947-100.pdf
Product MSDS
https://cdn.gentaur.com/products/37/865691/msds/bnub0947-100.pdf
CAS Number
9007-83-4
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