Anti-Beta-2 Microglobulin (B2M)(BBM.1)
Beta-2 microglobulin is a component of the class I major histocompatibility complex (MHC I) where it functions in antigen processing and presentation. Involved in the presentation of peptide antigens to the immune system. Human Beta-2 microglobulin is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes. This MAb is specific to human Beta-2 microglobulin and does not react with non-human primate cells. This antibody reacts with all cell types excluding erythrocytes. The detection of Beta-2 microglobulin in body fluids has been used as a tumor marker and for monitoring patients with HIV infection. _x000D_ Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors._x000D_ _x000D_
Product Specifications
Synonyms
B2M; Beta 2 microglobulin
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
B2M
Gene ID
567
NCBI Gene ID
534255
UniProt
P61769
Cellular Locus
Endoplasmic reticulum|Plasma membrane|Secreted (extracellular)
Host
Mouse
Species Reactivity
Human,Non-human primates
Immunogen
MOLT-4 human T cell line
Target Antigen
Beta-2 Microglobulin
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
BBM.1
Conjugation
Purified, BSA-free
Source
Animal
Applications
Flow, intracellular (verified) | IF (verified) | IHC, frozen (verified) | WB (verified)
Validated Applications
FC,IF,IHC,WB
Field of Research
Cancer, Immunology, Inflammation
Positive Control
HL-60 or HeLa cells. Melanomas and Lymphoma. Carcinoma of Stomach, Cervix, Endometrial, Kidney or Colon.
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
12 kDa
Additionnal Information
Shipping Conditions
Room temperature
Storage Conditions
-35°C to -5°C ; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/865388/datasheet/bnum0142-50.pdf
Product MSDS
https://cdn.gentaur.com/products/37/865388/msds/bnum0142-50.pdf
CAS Number
9007-83-4
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items