Anti-AFP (Alpha Fetoprotein)(C3)
Alpha-fetoprotein (AFP) is an oncofetal glycoprotein with a single chain of 70 kDa. This MAb is highly specific to AFP and shows no cross-reaction with other oncofetal antigens or serum albumin. AFP is normally synthesized in the liver, intestinal tract, and yolk sac of the fetus. Antibody to AFP has been shown to be useful in detecting hepatocellular carcinomas (HCC) and germ cell neoplasms, especially yolk sac tumors.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Specifications
Synonyms
Alpha-fetoglobulin; FETA; HPAFP
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
AFP
Gene ID
174
NCBI Gene ID
518808
UniProt
P02771
Cellular Locus
Cytoplasmic|Golgi apparatus
Host
Mouse
Species Reactivity
Dog,Human,Monkey,Pig
Immunogen
Alpha fetoprotein (AFP) purified from serum of a hepatoma patient
Target Antigen
AFP | Alpha-fetoprotein
Clonality
Monoclonal
Isotype
IgG2a κ
Clone
C3
Conjugation
Purified, with BSA
Disease
Tumor
Source
Animal
Applications
IHC, FFPE (verified)
Validated Applications
IHC,FFPE
Field of Research
Cancer, Developmental biology
Positive Control
Hep-G2 cells. Fetal liver or hepatocellular carcinoma
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
70 kDa
Additionnal Information
Shipping Conditions
Room temperature
Storage Conditions
4°C; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/864436/datasheet/bnub0354-500.pdf
Product MSDS
https://cdn.gentaur.com/products/37/864436/msds/bnub0354-500.pdf
CAS Number
9007-83-4
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