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Anti-Blood Group Antigen A(HE-193)

This antibody is applicable for staining ABO blood group A (monofucosyl and difucosyl A antigens with chain types 1, 2, 3, 4, 5, 6). It also recognizes Forssman antigen. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. Blood group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigen._x000D_ _x000D_ This antibody is available purified with BSA/azide at 200 ug/mL, or BSA/azide-free at 1 mg/mL.

Product Specifications

Synonyms

ABO Type A; Blood Group A; Forssman antigen

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

ABO

Gene ID

28

NCBI Gene ID

654423

UniProt

P16442

Cellular Locus

Plasma membrane

Host

Mouse

Species Reactivity

Human

Immunogen

Mixture of erythrocytes of blood group A and glycoprotein fraction isolated from the saliva of secretors with blood group A

Target Antigen

Blood Group A | Forssman Antigen

Clonality

Monoclonal

Isotype

IgM κ

Clone

HE-193

Conjugation

Purified, with BSA

Source

Animal

Applications

IHC, FFPE (verified)

Validated Applications

IHC,FFPE

Field of Research

Cancer, Hematology

Positive Control

KG1 cells or human colorectal carcinoma tissues.

Concentration

0.2 mg/mL

Buffer

PBS, 0.05% BSA, 0.05% azide

Molecular Weight

Multiple

Additionnal Information

Immunohistology formalin-fixed 0.5-1.0 ug/mL|Staining of formalin/paraffin tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min|Immunofluorescence 0.5-1 ug/mL|Optimal dilution for a specific application should be determined by user

Shipping Conditions

Room temperature

Storage Conditions

4°C; Stable at room temperature or 37°C (98°F) for 7 days.

Shelf Life

2 years

Product Datasheet

https://cdn.gentaur.com/products/37/864094/datasheet/bnub1064-500.pdf

Product MSDS

https://cdn.gentaur.com/products/37/864094/msds/bnub1064-500.pdf

CAS Number

9007-83-4

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