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Napsin A (Lung Adenocarcinoma Marker) (NAPSA/1238 + NAPSA/1239), CF647 conjugate, 0.1mg/mL

Napsin is a pepsin-like aspartic proteinase connected with maturation of surfactant protein B.There are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs.

Product Specifications

Synonyms

ASP4, Aspartyl protease 4, KAP, Kidney derived aspartic protease like protein (Kdap), NAP1, NAPA, Napsa, napsin A aspartic peptidase, Pronapsin A, SNAPA

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

NAPSA

Gene ID

9476

NCBI Gene ID

512843

UniProt

O96009

Swiss Prot

O96009

Host

Mouse

Species Reactivity

Human

Reactivity

Napsin-A

Immunogen

Recombinant human Napsin-A protein fragment (aa189-299) (exact sequence is proprietary)

Target Antigen

Napsin-A

Clonality

Monoclonal

Clone

NAPSA/1238 NAPSA/1239

Type

Primary

Source

Animal

Origin

Animal

Applications

IHC, FFPE (verified) |WB (verified)

Field of Research

Cancer, Proteases

Positive Control

Lung adenocarcinoma

Stability

2 years

Concentration

0.1 mg/mL

Buffer

PBS, 0.1% BSA, 0.05% azide

Molecular Weight

37 kDa

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Notes

Protect from light

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Product Datasheet

https://cdn.gentaur.com/products/37/863776/datasheet/bnc471254-500.pdf

Product MSDS

https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf

Fragment

IgG, kappa

Species

Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

Classification

0.05% sodium azide (CAS 26628-22-8)

CAS Number

9007-83-4

Conjugate

CF647

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