Anti-Human Immunoglobulin Gamma (IgG) Heavy Chain(IG217 + IG266), CF647 conjugate
This MAb is specific to heavy chain of IgG and shows minimal cross-reaction with heavy chains of other immunoglobulins. It is reactive with all subclasses of Gamma heavy chain(IgG1, IgG2a, IgG2b, IgG3). The most common feature of plasmacytomas, and certain non-Hodgkin's lymphomas is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant. Ab-3 is superb for staining of formalin-fixed tissues.
Product Specifications
Synonyms
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
IGHG
Gene ID
3500; 3501; 3502; 3503
NCBI Gene ID
510635
UniProt
P01857, P01859, P01860, P01861
Cellular Locus
Secreted (extracellular)
Host
Mouse
Species Reactivity
Human
Immunogen
Purified human IgG
Clonality
Monoclonal
Isotype
IgG1 κ
Clone
IG217 IG266
Conjugation
CF647
Disease
Tumor
Source
Animal
Applications
IHC, FFPE (verified)
Validated Applications
IHC,FFPE
Field of Research
Cancer, Immunology, Inflammation
Positive Control
293T, Raji or hPBL cells. Tonsil or Spleen
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
75 kDa
Additionnal Information
Shipping Conditions
Room temperature
Storage Conditions
4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/863473/datasheet/bnc471262-100.pdf
Product MSDS
https://cdn.gentaur.com/products/37/863473/msds/bnc471262-100.pdf
CAS Number
9007-83-4
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