Anti-Human Immunoglobulin Gamma (IgG) Heavy Chain(IG217 + IG266)
This MAb is specific to heavy chain of IgG and shows minimal cross-reaction with heavy chains of other immunoglobulins. It is reactive with all subclasses of Gamma heavy chain(IgG1, IgG2a, IgG2b, IgG3). The most common feature of plasmacytomas, and certain non-Hodgkin's lymphomas is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant. Ab-3 is superb for staining of formalin-fixed tissues.
Product Specifications
Synonyms
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
IGHG
Gene ID
3500; 3501; 3502; 3503
NCBI Gene ID
510635
UniProt
P01857, P01859, P01860, P01861
Cellular Locus
Secreted (extracellular)
Host
Mouse
Species Reactivity
Human
Immunogen
Purified human IgG
Clonality
Monoclonal
Isotype
IgG1 κ
Clone
IG217 IG266
Conjugation
Purified, BSA-free
Disease
Tumor
Source
Animal
Applications
IHC, FFPE (verified)
Validated Applications
IHC,FFPE
Field of Research
Cancer, Immunology, Inflammation
Positive Control
293T, Raji or hPBL cells. Tonsil or Spleen
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
75 kDa
Additionnal Information
Shipping Conditions
Room temperature
Storage Conditions
-35°C to -5°C ; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/863450/datasheet/bnum1262-50.pdf
Product MSDS
https://cdn.gentaur.com/products/37/863450/msds/bnum1262-50.pdf
CAS Number
9007-83-4
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