Anti-Fibronectin (8th Type III Repeat)(568), CF488A conjugate
The epitope of this antibody is located in the 8th type III repeat in the cell-binding region of fibronectin. Fibronectins are disulfide-linked, dimeric glycoproteins of ~440 kDa. They possess at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Fibronectins are involved in cell adhesion, tissue organization, and wound healing. Fibronectins are present in basement membranes, interstitial connective tissue matrix, and blood. Cellular fibronectin is widely distributed in the stroma of many malignant tumors. This MAb is excellent for staining of formalin-fixed, paraffin-embedded tissues.
Product Specifications
Synonyms
Cold insoluble globulin (CIG); FINC; FN1; FNZ; GFND; GFND2; LETS; Migration stimulating factor (MSF); Ugl-Y3
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
FN1
Gene ID
2335
NCBI Gene ID
203717
UniProt
P02751
Cellular Locus
Extracellular matrix
Host
Mouse
Species Reactivity
Human
Immunogen
High molecular weight proteins secreted by cultivated human fibroblasts
Target Antigen
Fibronectin
Clonality
Monoclonal
Isotype
IgG1 κ
Clone
568
Conjugation
CF488A
Source
Animal
Applications
IHC, FFPE (verified)
Validated Applications
IHC,FFPE
Field of Research
Cell adhesion, Extracellular matrix
Positive Control
SW156 cells. Kidney.
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
220 kDa (monomer); 440 kDa (dimer)
Additionnal Information
Shipping Conditions
Room temperature
Storage Conditions
4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/863232/datasheet/bnc880351-500.pdf
Product MSDS
https://cdn.gentaur.com/products/37/863232/msds/bnc880351-500.pdf
CAS Number
9007-83-4
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