11(Z),14(Z)-Eicosadienoic acid
Product Specifications
UNSPSC Description
11(Z),14(Z)-Eicosadienoic acid is a unsaturated fattly acid that inhibits [3H] leukotriene B4 (LTB4) binding to pig neutrophil membranes with a Ki of 3 μM. 11(Z),14(Z)-Eicosadienoic acid has inflammatory activities[1][2].
Target Antigen
Leukotriene Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/11-z-14-z-eicosadienoic-acid.html
Solubility
10 mM in DMSO
Smiles
CCCCC/C=C\C/C=C\CCCCCCCCCC(O)=O
Molecular Weight
308.50
References & Citations
[1]Carballeira NM, et al. Identification of naturally occurring trans, trans delta 5,9 fatty acids from the sponge Plakortis halichondroides. Lipids. 1990 Dec;25(12):835-40. |[2]Yagaloff KA, et al. Essential fatty acids are antagonists of the leukotriene B4 receptor. Prostaglandins Leukot Essent Fatty Acids. 1995 May;52(5):293-7.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-149589/11-Z-14-Z-Eicosadienoic-acid-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-149589/
Clinical Information
No Development Reported
CAS Number
5598-38-9
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