ALK5-IN-83
Product Specifications
UNSPSC Description
ALK5-IN-83 (compound 13b) is a ALK5 inhibitor with the IC50 of 0.13 μM. ALK5-IN-83 inhibits TGF-β1-induced Smad2 phosphorylation and cell motility in A549 cells[1].
Target Antigen
TGF-beta/Smad
Type
Reference compound
Related Pathways
Stem Cell/Wnt;TGF-beta/Smad
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/alk5-in-83.html
Smiles
CCCCS(=O)(NCC1=NC(C2=CN3N=CN=C3C=C2)=C(N1)C4=CC=CC(C)=N4)=O
Molecular Weight
425.51
References & Citations
[1]Ding SY, et al. Synthesis and biological evaluation of sulfonamide derivatives containing imidazole moiety as ALK5 inhibitors. Mol Divers. 2024 Aug 30.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-168607/ALK5-IN-83-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-168607/
Clinical Information
No Development Reported
Curated Selection
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