YT-8-8
Product Specifications
UNSPSC Description
YT-8-8 is a ligand of p62-ZZ domain. YT-8-8 can activate p62-dependent selective macroautophagy. YT-8-8 can be used for AUTOTAC design[1].
Target Antigen
AUTOTACs; p62
Type
Reference compound
Related Pathways
Autophagy;PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/yt-8-8.html
Smiles
OCCNCCNCC1=CC(OCC2=CC=C(F)C=C2)=CC=C1
Molecular Weight
318.39
References & Citations
[1]Ji CH, et al. The AUTOTAC chemical biology platform for targeted protein degradation via the autophagy-lysosome system. Nat Commun. 2022 Feb 16;13(1):904.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-161737/YT-8-8-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-161737/
Clinical Information
No Development Reported
CAS Number
892572-23-5
Curated Selection
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