SHP2-IN-34
SHP2-IN-34 (compound A8) is a phenyl urea SHP2 inhibitor with anti-cancer activity. SHP2-IN-34 significantly suppresses tumor growth in CT26 mouse model[1].
Product Specifications
CAS Number
[2924065-12-1]
UNSPSC
12352005
Target
SHP2
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/shp2-in-34.html
Smiles
O=C(NC1=C(Cl)C(SC2=NC=C(N3CCC(C)(CC3)N)N=C2N)=CC=C1)NC4=CC(Cl)=CC=C4
Molecular Formula
C23H25Cl2N7OS
Molecular Weight
518.46
References & Citations
[1]Wang K, et al. Discovery of novel phenyl urea SHP2 inhibitors with anti-colon cancer and potential immunomodulatory effects. Eur J Med Chem. 2025 Jan 5;281:117036.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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