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BMY-21502

BMY-21502 (BMS-181168) is a pyrrolidinone derivative with memory- and cognition-enhancing activities. BMS-181168 attenuates hypoxia-induced deterioration in brain function, as delta/theta decreases, alpha activity increases and the centroid of the combined delta/theta waves is accelerated[1].

Product Specifications

CAS Number

[123259-91-6]

Product Name Alternative

BMS-181168

UNSPSC

12352005

Target

Drug Derivative

Type

Reference compound

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/bmy-21502.html

Purity

98.98

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1N(CC2CCN(CC2)C3=NC(C(F)(F)F)=NC=C3)CCC1

Molecular Formula

C15H19F3N4O

Molecular Weight

328.33

References & Citations

[1]Saletu B, et al. BMS-181168 for protection of the human brain against hypoxia: double-blind, placebo-controlled EEG mapping studies. Pharmacopsychiatry. 1994 Sep;27 (5) :189-97.|[2]Saletu B, et al. BMS-181168 for protection of the human brain against hypoxia: double-blind, placebo-controlled EEG mapping studies. Pharmacopsychiatry. 1994 Sep;27 (5) :189-97.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 2

Available Sizes

Curated Selection

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