SLV310
Product Specifications
UNSPSC Description
SLV310 is an orally active dopamine D2 receptor antagonist (Ki: 5 nM) and serotonin reuptake receptor inhibitor. SLV310 antagonizes Apomorphine (HY-12723) induced climbing behaviour and 5-HTP (HY-N0122) induced serotonin syndrome like behaviour in mice (ED50: 5.6 and 5.9 mg/kg, p.o.). SLV310 is an antipsychotic compound and can be used for schizophrenia research[1].
Target Antigen
Dopamine Receptor; Serotonin Transporter
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/slv310.html
Smiles
O=C1C2=C(C(N1CCCCN3CC=C(CC3)C4=CNC5=C4C=C(F)C=C5)=O)C=CC=C2
Molecular Weight
417.48
References & Citations
[1]van Hes R,et al. SLV310, a novel, potential antipsychotic, combining potent dopamine D2 receptor antagonism with serotonin reuptake inhibition. Bioorg Med Chem Lett. 2003 Feb 10;13(3):405-8.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-106194/SLV310-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-106194/
Clinical Information
Phase 2
CAS Number
264869-71-8
Curated Selection
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