WYRGRL
Product Specifications
UNSPSC Description
WYRGRL, a collagen II-targeting peptide, can bind to collagen II α1. WYRGRL is a short cartilage-targeting peptide sequence. WYRGRL leads to about 72-fold increase of cartilage-targeting efficiency for the peptide-functionalized nanoplatform in vivo[1][2].
Target Antigen
MMP
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/wyrgrl.html
Smiles
O=C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)[C@H](CC2=CNC3=CC=CC=C23)N
Molecular Weight
849.98
References & Citations
[1]Kai Ren, et al. Zwitterionic polymer modified xanthan gum with collagen II-binding capability for lubrication improvement and ROS scavenging. Carbohydr Polym. 2021 Nov 15:274:118672. |[2]Dominique A Rothenfluh, et al. Biofunctional polymer nanoparticles for intra-articular targeting and retention in cartilage. Nat Mater. 2008 Mar;7(3):248-54.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P10739/WYRGRL-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P10739/
Clinical Information
No Development Reported
CAS Number
1021155-39-4
Curated Selection
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