Cyclooxygenase 1, sheep
Product Specifications
UNSPSC Description
Cyclooxygenase 1, sheep (COX-1) is a 71 kDa membrane bound protein predominantly present in endoplasmic reticulum. Cyclooxygenase 1 has three domains, the epidermal growth factor (EGF) like domain, enzymatic and membrane binding domain. Cyclooxygenase 1 mediates prostaglandin synthesis and is modulated by anti-inflammatory nonsteroidal drugs[1].
Target Antigen
Endogenous Metabolite
Type
Enzyme
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/cyclooxygenase-1-sheep.html
Solubility
10 mM in DMSO
Smiles
[Cyclooxygenase 1, sheep]
References & Citations
[1]Katrina M Mirabito Colafella, et al. Aspirin for the prevention and treatment of pre-eclampsia: A matter of COX-1 and/or COX-2 inhibition? Basic Clin Pharmacol Toxicol. 2020 Aug;127(2):132-141.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-E70229/Cyclooxygenase-1-sheep-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-E70229/Cyclooxygenase-1-sheep-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
329967-85-3
Curated Selection
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