Cyclooxygenase 1, sheep
Cyclooxygenase 1, sheep (COX-1) is a 71 kDa membrane bound protein predominantly present in endoplasmic reticulum. Cyclooxygenase 1 has three domains, the epidermal growth factor (EGF) like domain, enzymatic and membrane binding domain. Cyclooxygenase 1 mediates prostaglandin synthesis and is modulated by anti-inflammatory nonsteroidal drugs[1].
Product Specifications
CAS Number
[329967-85-3]
Product Name Alternative
COX-1
UNSPSC
12352204
Target
Endogenous Metabolite
Type
Enzyme
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/cyclooxygenase-1-sheep.html
Solubility
10 mM in DMSO
Smiles
[Cyclooxygenase1,sheep]
References & Citations
[1]Katrina M Mirabito Colafella, et al. Aspirin for the prevention and treatment of pre-eclampsia: A matter of COX-1 and/or COX-2 inhibition? Basic Clin Pharmacol Toxicol. 2020 Aug;127 (2) :132-141.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Enzyme
Clinical Information
No Development Reported
Curated Selection
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