Cyclooxygenase 1, sheep

Cyclooxygenase 1, sheep (COX-1) is a 71 kDa membrane bound protein predominantly present in endoplasmic reticulum. Cyclooxygenase 1 has three domains, the epidermal growth factor (EGF) like domain, enzymatic and membrane binding domain. Cyclooxygenase 1 mediates prostaglandin synthesis and is modulated by anti-inflammatory nonsteroidal drugs[1].

Product Specifications

CAS Number

[329967-85-3]

Product Name Alternative

COX-1

UNSPSC

12352204

Target

Endogenous Metabolite

Type

Enzyme

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/cyclooxygenase-1-sheep.html

Solubility

10 mM in DMSO

Smiles

[Cyclooxygenase1,sheep]

References & Citations

[1]Katrina M Mirabito Colafella, et al. Aspirin for the prevention and treatment of pre-eclampsia: A matter of COX-1 and/or COX-2 inhibition? Basic Clin Pharmacol Toxicol. 2020 Aug;127 (2) :132-141.