Aglepristone
Product Specifications
UNSPSC Description
Aglepristone is a synthetic steroidal antiprogestin with abortifacient activity. Aglepristone is used exclusively as an abortifacient in pregnant animals. Aglepristone has been shown to be a safe and effective abortifacient in the second trimester of pregnancy. Aglepristone causes termination of pregnancy and does not cause fetal resorption. During aglepristone treatment, an increase in plasma concentrations of prolactin was observed, while progesterone levels remained unchanged. The use of aglepristone also resulted in early arrest of corpus luteum function and a shortening of the estrus interval[1].
Target Antigen
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/aglepristone.html
Smiles
C[C@@]12[C@](CC[C@@]2(O)/C=C\C)([H])[C@@]3([H])C([C@@H](C4=CC=C(C=C4)N(C)C)C1)=C5C(CC3)=CC(CC5)=O
Molecular Weight
431.61
References & Citations
[1]Termination of mid-gestation pregnancy in bitches with aglepristone, a progesterone receptor antagonist
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-135730/Aglepristone-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-135730/
Clinical Information
No Development Reported
CAS Number
124478-60-0
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