Ametantrone (acetate)
Ametantrone acetate (NSC 196473 acetate) is an antineoplastic drug with topoisomerase II inhibitory activity. Ametantrone acetate causes covalent cross-linking of DNA. The pharmacokinetic profile of Ametantrone acetate has been confirmed in clinical trials, and its elimination pathway in the body indicates the existence of a major metabolic pathway[1].
Product Specifications
CAS Number
[70711-40-9]
Product Name Alternative
NSC 196473 (acetate) ; NSC 290813 (acetate)
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ametantrone-acetate.html
Smiles
O=C1C2=C(C(C3=C(C=CC(NCCNCCO)=C13)NCCNCCO)=O)C=CC=C2.CC(O)=O.CC(O)=O
Molecular Formula
C26H36N4O8
Molecular Weight
532.59
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
