YM-44778
YM-44778 is a neurokinin receptor antagonist. The pKi values for NK1, NK2 and NK3 are 8.08, 8.55 and 8.24, respectively. YM-44778 inhibits the increase of bladder pressure induced by substance [Sar9, Met (O2) 11] -P (HY-P1012) in anestheticized rats[1].
Product Specifications
CAS Number
[173941-74-7]
UNSPSC
12352005
Target
Neurokinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ym-44778.html
Smiles
O=C(C1=CC(OC)=C(C(OC)=C1)OC)N(C)CC(CCN2CCC3(NC(CC4=C3C=CC=C4)=O)CC2)C5=CC=C(C(Cl)=C5)Cl
Molecular Formula
C34H39Cl2N3O5
Molecular Weight
640.60
References & Citations
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-120167/YM-44778-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-120167/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Lentiviral mouse Pptc7 shRNA (UAS) - Lentiviral mouse Pptc7 shRNA (UAS, iRFP) (100)
