Progesterone-d9

Progesterone-d9 is the deuterium labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.

Product Specifications

CAS Number

[15775-74-3]

Product Name Alternative

Pregn-4-ene-3,20-dione-d9

UNSPSC

12352211

Hazard Statement

H225, H302+H332, H319

Target

Endogenous Metabolite; Progesterone Receptor

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Field of Research

Cardiovascular Disease; Cancer

Purity

99.97

Solubility

DMSO : 50 mg/mL (ultrasonic; warming)

Smiles

C[C@]12[C@]([H])([C@@]3(CC([2H])(C4=C(C(C([2H])(C[C@@]4([C@]3(CC2)[H])C)[2H])=O)[2H])[2H])[H])CC[C@@]1(C(C([2H])([2H])[2H])=O)[2H]

Molecular Formula

C21H21D9O2

Molecular Weight

323.52

Precautions

H225, H302+H332, H319

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Schindler AE, et al. Classification and pharmacology of progestins. Maturitas. 2003 Dec 10;46 Suppl 1:S7-S16.|[3]Zava DT, et al. Estrogen and progestin bioactivity of foods, herbs, and spices. Proc Soc Exp Biol Med. 1998 Mar;217 (3) :369-78.|[4]Komesaroff PA, et al. Effects of wild yam extract on menopausal symptoms, lipids and sex hormones in healthy menopausal women. Climacteric. 2001 Jun;4 (2) :144-50.|[5]Girling JE, et al. Progesterone, but not estrogen, stimulates vessel maturation in the mouse endometrium. Endocrinology. 2007 Nov;148 (11) :5433-41. Epub 2007 Aug 9.