p53 Activator 5
Product Specifications
UNSPSC Description
p53 Activator 5 (compound 134A) is a potent p53 activator with a SC150 value of [1]. p53 Activator 5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Target Antigen
MDM-2/p53
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/p53-activator-5.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
COC1=CC(C(F)(F)F)=CC=C1NCC#CC2=CC3=C(C=CC=C3N[C@@H](CC4)CC[C@H]4N(C)C)N2CC(F)(F)F
Molecular Weight
566.58
References & Citations
[1]VU, Binh, et al. Methods and compounds for restoring mutant p53 function, WO2021061643.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-148404/p53-Activator-5-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-148404/p53-Activator-5-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2636840-37-2
Available Sizes
Curated Selection
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