Frataxin-IN-1
Product Specifications
UNSPSC Description
Frataxin-in-1 (Compound (+)-11) is a Frataxin inhibitor with IC50 value of 45 μM, which can be used in the study of Friedreich's ataxia (FRDA)[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/frataxin-in-1.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=CC(=C1OC)C(C2=CC3=C(C=C2O)OCO3)N4CCOCC4
Molecular Weight
373.40
References & Citations
[1]Lavecchia A, et al. Discovery of a novel small molecule inhibitor targeting the frataxin/ubiquitin interaction via structure-based virtual screening and bioassays. J Med Chem. 2013 Apr 11;56(7):2861-73.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W509563/Frataxin-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W509563/
Clinical Information
No Development Reported
CAS Number
102616-64-8
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