STING agonist-7

STING agonist-7 is a non-nucleotide STING agonist. STING agonist-7 binds selectively to mouse STING but not human STING. STING agonist-7 penetrates cell membrane poorly[1].

Product Specifications

CAS Number

[2767442-46-4]

UNSPSC

12352005

Target

STING

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/sting-agonist-7.html

Purity

97.22

Solubility

DMSO : 62.5 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=CC2=C1OC(CNC(C3=C4N=CC=CN4N=C3)=O)=C2)O

Molecular Formula

C17H12N4O4

Molecular Weight

336.30

References & Citations

[1]Emily C Cherney, et al. Discovery of Non-Nucleotide Small-Molecule STING Agonists via Chemotype Hybridization. J Med Chem. 2022 Feb 24;65 (4) :3518-3538.