JAK2 Polyclonal Antibody

Rabbit Anti-JAK2 Polyclonal Antibody

Product Specifications

Background

Tyrosine-protein kinase JAK2 is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

CAS Number

9007-83-4

Product Name Alternative

JAK2; Tyrosine-protein kinase JAK2; Janus kinase 2; JAK-2

Gene ID

3717

Accession Number

O60674

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human JAK2 around the non-phosphorylation site of Y1007

Clonality

Polyclonal

Tag

Tyrosine-protein kinase JAK2

Applications

IF, WB, IHC, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

130kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

JAK2 Polyclonal Antibody detects endogenous levels of JAK2 protein.

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF 1:50-200; WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; Not yet tested in other applications