LC3A Mouse Monoclonal Antibody (5G10)
Mouse Anti-LC3A Mouse Monoclonal Antibody (5G10)
Product Specifications
Background
MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by MAP1LC3A (microtubule associated protein 1 light chain 3 alpha) is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for MAP1LC3A. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis.
CAS Number
9007-83-4
Product Name Alternative
Microtubule-associated proteins 1A/1B light chain 3A; Autophagy-related protein LC3 A; Autophagy-related ubiquitin-like modifier LC3 A; MAP1 light chain 3-like protein 1; MAP1A/MAP1B light chain 3 A; MAP1A/MAP1B LC3 A; Microtubule-associated protein 1 light chain 3 alpha
Gene ID
84557
Accession Number
Q9H492
Reactivity
Human, Rat, Mouse
Immunogen
Synthetic Peptide of LC3A
Clonality
Monoclonal
Tag
LC3A
Applications
WB, IF, IHC
Purification Method
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Molecular Weight
14,16kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
LC3A protein detects endogenous levels of LC3A.
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:1000-2000; IHC 1:100-200; IF 1:200
Other Product Names
Microtubule-associated proteins 1A/1B light chain 3A; Autophagy-related protein LC3 A; Autophagy-related ubiquitin-like modifier LC3 A; MAP1 light chain 3-like protein 1; MAP1A/MAP1B light chain 3 A; MAP1A/MAP1B LC3 A; Microtubule-associated protein 1 light chain 3 alpha
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Mouse
Accession Number URL
http://www.uniprot.org/uniprot/Q9H492
Isotype
Mouse IgG1
Curated Selection
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