Hsp110-STAT3 interaction-IN-2
Product Specifications
UNSPSC Description
Hsp110-STAT3 interaction-IN-2 (compound 10b) is a Hsp110-STAT3 interaction disruptor. Hsp110-STAT3 interaction-IN-2 can be used in pulmonary arterial hypertension (PAH) related research[1].
Target Antigen
HSP; STAT
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;JAK/STAT Signaling;Metabolic Enzyme/Protease;Stem Cell/Wnt
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/hsp110-stat3-interaction-in-2.html
Smiles
OC1=CC=CC(C2=NC(C3=C(OCC4=CC=CC(C)=C4)N=C(N(C)N=C5C(F)(F)F)C5=C3)=NO2)=C1
Molecular Weight
481.43
References & Citations
[1]Li M, et al. Design, synthesis and optimization of pyrazolo[3,4-b] pyridine derivatives as Hsp110-STAT3 interaction disruptors for the treatment of pulmonary arterial hypertension. Bioorg Chem. 2024 Oct 14;153:107888.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-168178/Hsp110-STAT3-interaction-IN-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-168178/
Clinical Information
No Development Reported
Curated Selection
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