DLRIE

DLRIE is a cationic lipid that can be used for the synthesis of liposome GAP-DLRIE. GAP-DLRIE can be used to enhance the delivery and expression of plasmid DNA. DLRIE can be used for delivery of nucleic acids[1][2].

Product Specifications

CAS Number

[199171-54-5]

UNSPSC

12352211

Hazard Statement

H315, H319, H335

Target

Liposome

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/dlrie.html

Purity

99.41

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

OCC[N+](C)(CC(COCCCCCCCCCCCC)OCCCCCCCCCCCC)C.[Br-]

Molecular Formula

C31H66BrNO3

Molecular Weight

580.76

Precautions

H315, H319, H335

References & Citations

[1]Wheeler CJ, et al. A novel cationic lipid greatly enhances plasmid DNA delivery and expression in mouse lung. Proc Natl Acad Sci U S A. 1996 Oct 15;93 (21) :11454-9.|[2]Felgner PL, et al. Improved cationic lipid formulations for in vivo gene therapy. Ann N Y Acad Sci. 1995 Nov 27;772:126-39.