Calcifediol-d6

Calcifediol-d6 is the deuterium labeled Calcifediol. Calcifediol, a major circulating metabolite of vitamin D3, is a potent VDR ligand[1][2].

Product Specifications

CAS Number

[78782-98-6]

Product Name Alternative

25-hydroxy Vitamin D3-d6

UNSPSC

12352211

Hazard Statement

H301

Target

Isotope-Labeled Compounds; VD/VDR

Type

Isotope-Labeled Compounds

Related Pathways

Others; Vitamin D Related/Nuclear Receptor

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Purity

99.09

Solubility

DMSO : ≥ 100mg/mL

Smiles

O[C@@H](CCC/1=C)CC1=C\C=C2[C@@](CC[C@@H]3[C@@H](CCCC(C([2H])([2H])[2H])(C([2H])([2H])[2H])O)C)([H])[C@]3(C)CCC\2

Molecular Formula

C27H38D6O2

Molecular Weight

406.67

Precautions

H301

References & Citations

[1]Trifu V, et al. Cortexolone 17α-propionate 1% cream, a new potent antiandrogen for topical treatment of acne vulgaris. A pilot randomized, double-blind comparative study vs. placebo and tretinoin 0•05% cream. Br J Dermatol. 2011 Jul;165 (1) :177-83.|[2]Celasco G, et al. Biological profile of cortexolone 17alpha-propionate (CB-03-01), a new topical and peripherally selective androgen antagonist. Arzneimittelforschung. 2004;54 (12) :881-6.|[3]Trifu V, et al. Cortexolone 17-propionate 1% cream, a new potent antiandrogen for topical treatment of acne vulgaris. A pilot randomized, double-blind comparative study vs. placebo and tretinoin 005% cream. Br J Dermatol. 2011 Jul;165 (1) :177-83.