Human TROP-2 / TACSTD2 (88-274) Protein, His Tag
Human TROP-2 (88-274) Protein, His Tag (TR2-H52H6) is expressed from human 293 cells (HEK293) . It contains AA Thr 88 - Thr 274 (Accession # P09758-1) .
Product Specifications
Background
TROP-2 is a single-copy gene in human cells, and encodes a type-1 transmembrane glycoprotein which is over-expressed in various malignancies, also referred to as tumor associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1. TROP-2 is related to epithelial cell adhesion molecule (EpCAM), also called TROP-1, gp40, and KSA. Trop-1 and Trop-2 are homologous to serum IGF-II-binding proteins and appear as signal transducers. Thus, they likely represent novel cell-surface receptors and may play a role in regulating the growth of carcinoma cells.
Specifications
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 23.5 kDa. The protein migrates as 33-43 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
P09758-1
Expression Region
Thr 88 - Thr 274
Host
HEK293
Target
TROP-2
Conjugation
Unconjugated
Tag
C-10xHis
Source
Human
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
90%
Bioactivity
Immobilized Human TROP-2 (88-274) Protein, His Tag (Cat. No. TR2-H52H6) at 1 μg/mL (100 μL/well) can bind Mouse Monoclonal Antibody Against Human TROP-2 Protein,Mouse IgG1 with a linear range of 0.2-4 ng/mL (QC tested).
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
23.5 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
200ug*5
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/TR2-H52H6.pdf
Species
Human
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