Cynomolgus DLL3 (27-488) Protein, His Tag
Cynomolgus DLL3 (27-488), His Tag (DL3-C52H9) is expressed from human 293 cells (HEK293) . It contains AA Ala 27 - Arg 488 (Accession # A0A2K5WSR1-1) .
Product Specifications
Background
Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands.May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. DLL3 protein is expressed on the surface of tumor cells but not in normal adult tissues.
Specifications
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 50.0 kDa. The protein migrates as 50-55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
A0A2K5WSR1-1
Expression Region
Ala 27 - Arg 488
Host
HEK293
Target
DLL3
Conjugation
Unconjugated
Tag
C-10xHis
Source
Cynomolgus
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
90%
Bioactivity
Immobilized Cynomolgus DLL3 (27-488), His Tag (Cat. No. DL3-C52H9) at 1 μg/mL (100 μL/well) can bind Anti-DLL3 Antibody (specific Binding DSL of DLL3), Human IgG1 with a linear range of 0.1-3 ng/mL (QC tested).
Format
Powder
Buffer
PBS, 0.2 M Arginine, pH7.4
Additives
Trehalose
Molecular Weight
50.0 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/DL3-C52H9.pdf
Species
Cynomolgus
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