Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Human GITR / TNFRSF18 Protein, Fc Tag

Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.

Product Specifications

Background

Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.

Specifications

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 41.0 kDa. The protein migrates as 45-47 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

Q9Y5U5-1

Expression Region

Gln 26 - Glu 161

Host

HEK293

Target

GITR

Conjugation

Unconjugated

Tag

C-Fc

Source

Human

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

95%

Bioactivity

Immobilized Human GITR, Fc Tag (Cat. No. GIR-H5254) at 2 μg/mL (100 μL/well) can bind Biotinylated Human GITR Ligand, Avitag,Fc Tag (Cat. No. GIL-H82F8) with a linear range of 4-63 ng/mL (QC tested).

Format

Powder

Buffer

Tris with Glycine, Arginine and NaCl, pH7.5

Additives

Trehalose

Molecular Weight

41.0 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

100ug*1

Host or Source

HEK293

Species

Human

Protein ID

Q9Y5U5-1

Preservative

Trehalose

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

LIN9 (Lin-9 Homolog (C. Elegans) EMBL CAI14231.1, Lin-9 Homolog (C. Elegans) )
484815 100 µL

LIN9 (Lin-9 Homolog (C. Elegans) EMBL CAI14231.1, Lin-9 Homolog (C. Elegans) )

Ask
View Details
SLFN12 antibody - N-terminal region
MBS3213170-01 0.1 mL

SLFN12 antibody - N-terminal region

Ask
View Details
SLFN12 antibody - N-terminal region
MBS3213170-02 5x 0.1 mL

SLFN12 antibody - N-terminal region

Ask
View Details
2510002D24Rik Mouse siRNA Oligo Duplex (Locus ID 72307)
SR401287 1 Kit

2510002D24Rik Mouse siRNA Oligo Duplex (Locus ID 72307)

Ask
View Details
Vkorc1 (NM_178600) Mouse Tagged ORF Clone Lentiviral Particle
MR201263L3V 200 µL

Vkorc1 (NM_178600) Mouse Tagged ORF Clone Lentiviral Particle

Ask
View Details