H2TMpyP-2 (chloride)

H2TMpyP-2 (tetrakis (2-N-methylpyridyl) porphine) chloride is an active photosensitizer with strong absorption properties in the visible to near-infrared region and excellent singlet oxygen quantum yield. Captisol-TMPyP complexes can be used in supramolecular nanosynthesis to increase singlet oxygen production, improve photostability and better photosensitization, and support photodynamic therapy activity. The Captisol:TMPyP complex also exhibited antibacterial activity against Escherichia coli and was cytotoxic against lung cancer A549 cells[1].

Product Specifications

CAS Number

[129051-18-9]

Product Name Alternative

Tetrakis (2-N-methylpyridyl) porphine (chloride)

UNSPSC

12171500

Hazard Statement

H302, H315, H319, H335

Target

Biochemical Assay Reagents; Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/h2tmpyp-2-chloride.html

Purity

99.0

Solubility

DMSO : 4.17 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

C[N+]1=CC=CC=C1C2=C3C=CC(C(C4=CC=CC=[N+]4C)=C5C=CC(N5)=C(C6=CC=CC=[N+]6C)C(C=C7)=NC7=C(C8=CC=CC=[N+]8C)C9=CC=C2N9)=N3.[Cl-].[Cl-].[Cl-].[Cl-]

Molecular Formula

C44H38Cl4N8

Molecular Weight

820.64

Precautions

H302, H315, H319, H335

References & Citations

[1]Khurana R, et al. Supramolecular Nanorods of (N-Methylpyridyl) Porphyrin With Captisol: Effective Photosensitizer for Anti-bacterial and Anti-tumor Activities. Front Chem. 2019 Jun 21;7:452.