(-) -Integerrimine

(-) -Integerrimine, a pyrrolizidine alkaloid, has antiulcerogenic activity. (-) -Integerrimine is also a mutagenic and weakly clastogenic agent in Drosophila[1][2].

Product Specifications

CAS Number

[480-79-5]

UNSPSC

12352005

Hazard Statement

H300+H310+H330

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/minus-integerrimine.html

Solubility

10 mM in DMSO

Smiles

O=C1O[C@@]2([H])[C@]3([H])N(CC=C3COC([C@](O)([C@@H](C/C1=C\C)C)C)=O)CC2

Molecular Formula

C18H25NO5

Molecular Weight

335.39

Precautions

P260-P262-P264-P270-P271-P280-P284-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501

References & Citations

[1]V R Campesato, et al. Recombinagenic activity of integerrimine, a pyrrolizidine alkaloid from Senecio brasiliensis, in somatic cells of Drosophila melanogaster. Environ Mol Mutagen. 1997;29 (1) :91-7.|[2]Walber Toma, et al. Modulation of gastrin and epidermal growth factor by pyrrolizidine alkaloids obtained from Senecio brasiliensis in acute and chronic induced gastric ulcers. Can J Physiol Pharmacol. 2004 May;82 (5) :319-25.