Perfluoroenanthic acid
Product Specifications
UNSPSC Description
Perfluoroenanthic acid (Perfluoroheptanoic acid) is a type of perfluoroalkyl substance (PFAS) that can negatively impact the development of seminiferous tubules and m6A RNA methylation in the testes of offspring mice when exposed during pregnancy, consequently disrupting spermatogenesis and leading to reproductive toxicity. Perfluoroenanthic acid alters the morphology of dendritic spines and synaptic formation in primary cortical neuron cultures, enhancing neuronal activity and synaptic transmission, and increasing the expression of excitatory synapse-related proteins Synaptophysin and PSD95[1][2].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Neurological Disease
Purity
97.89
Smiles
O=C(O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F
Molecular Weight
364.06
References & Citations
[1]Yijie Zhou, et al. Effect of prenatal perfluoroheptanoic acid exposure on spermatogenesis in offspring mice. Ecotoxicol Environ Saf. 2023 Jul 15:260:115072.|[2]Moon Yi Ko, et al. Differential regulations of neural activity and survival in primary cortical neurons by PFOA or PFHpA. Chemosphere. 2024 Mar:352:141379.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Clinical Information
No Development Reported
CAS Number
375-85-9
Curated Selection
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