Phenylbiguanide (hydrochloride)
Product Specifications
UNSPSC Description
Phenylbiguanide hydrochloride is a 5-HT3 receptor selective agonist with an EC50 of 3.0±0.1 μM.
Target Antigen
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/phenylbiguanide-hydrochloride.html
Purity
99.80
Solubility
10 mM in DMSO
Smiles
NC(NC(NC1=CC=CC=C1)=N)=N.Cl
Molecular Weight
213.67
References & Citations
[1]Mair ID, et al. Pharmacological characterization of a rat 5-hydroxytryptamine type3 receptor subunit (r5-HT<sub>3A(b)</sub>) expressed in <i>Xenopus laevis</i> oocytes. Br J Pharmacol. 1998 Aug;124(8):1667-74.|[2]Ataee R, et al. Study of 5HT3 and HT4 receptor expression in HT29 cell line and human colon adenocarcinoma tissues. Arch Iran Med. 2010 Mar;13(2):120-5.|[3]de Vries A, et al. Characterisation of c-Fos expression in the central nervous system of mice following right atrialinjections of the 5-HT3 receptor agonist Phenylbiguanide. Auton Neurosci. 2005 Dec 30;123(1-2):62-75.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-101331A/Phenylbiguanide-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-101331A/
Clinical Information
No Development Reported
CAS Number
55-57-2
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