Nolatrexed
Product Specifications
UNSPSC Description
Nolatrexed (AG 337 free base) is a compound with antifolate activity, high oral bioavailability, and major toxicity at inhibitory doses is gastrointestinal reactions. It can be safely taken orally at specific doses for inhibition, with effects on platelets and neutrophils.
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/nolatrexed.html
Smiles
O=C1N=C(NC2=CC=C(C)C(SC3=CC=NC=C3)=C12)N
Molecular Weight
284.34
References & Citations
[1]Phase I studies with the nonclassical antifolate nolatrexed dihydrochloride (AG337, THYMITAQ) administered orally for 5 days
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-13714/Nolatrexed-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-13714/
Clinical Information
Phase 3
CAS Number
147149-76-6
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